注册本刊作者作者投稿查稿
专家远程审稿编辑在线审稿
编务办公专区主编办公专区
下载文档
工作动态
联系方式
发行周期:
月刊
主管单位:
上海市卫生健康委员会
主办单位:
上海市医学会
编辑出版:
《上海医学》编辑部
联系地址:
上海市北京西路1623号
邮编:
200040
电话:
021-62178606
传真:
021-62178606
邮箱:
smasmj@shsma.org.cn
ISSN:
ISSN0253-9934
CN:
CN31-1366/R
收款账号:
1001255309008900719
账户名:
上海市医学会
开户行:
工商银行上海市静安寺支行
友情链接

当前位置：首页 > 过刊浏览->2012年第1期

2型糖尿病患者视网膜病变与贫血的关系
Relationship between diabetic retinopathy and anemia in patients with type 2 diabetes mellitus

浏览(2735) 下载(0)

DOI:
作者:
何斌斌，魏丽，包玉倩，贾伟平
He Binbin, Wei Li, Bao Yuqian,Jia Weiping
作者单位:
上海交通大学附属第六人民医院
Department of Endocrinology and Metabolism, Shanghai Jiaotong University Affiliated Sixth People’s Hospital Shanghai, China
关键词:
糖尿病，2型；糖尿病视网膜病变；贫血
Diabetes mellitus, type 2; diabetic retinopathy; anemia
摘要:
目的 探讨2型糖尿病(T2DM)患者视网膜病变(DR)与贫血之间的关系。 方法 对2009例2型糖尿病患者进行体脂参数、血压、血糖、血脂、血红蛋白、C反应蛋白(CRP)、24h尿微量白蛋白等测定，同时对眼底进行检查。根据眼底检查结果分为无视网膜病变(non-diabetic retinopathy, NDR)组和DR组，贫血则依据国内诊断贫血标准进行诊断。分析贫血与DR发生率的相关性。 结果 2型糖尿病患者中，合并贫血组DR的发生率明显高于无贫血组( P<0.01)，DR组患者贫血的发生率明显高于NDR组患者( P<0.01)。 Logistic回归分析显示，在校正性别、年龄、病程、体重指数、血脂、HbA1C、收缩压、舒张压、CRP、24h尿微量白蛋白等因素后，2型糖尿病患者合并贫血发生DR的OR值为1.952 (95% CI 1.273~2.995; P=0.002)。 结论 贫血是DR发生的一个重要的危险因素。
Objective The purpose of this study is to investigate the relationship between diabetic retinopathy (DR) and anemia in Chinese patients with type 2 diabetes mellitus (T2DM). Methods 2009 hospitalized patients with type 2 diabetes mellitus were enrolled in this study. The case history, physical examination and biochemical tests were conducted. All patients underwent eye examination and were divided into two groups based on the results of fundus examination: non-diabetic retinopathy (NDR) group and DR group. According to Chinese anemia criteria, anemia was defined as a hemoglobin (Hb) concentration of < 12 g/dl in men and < 11 g/dl in women. Results The prevalence of DR is higher in patients with anemia than those without (P<0.01), while the prevalence of anemia is higher in patients with DR than those without (P<0.01). Logistic regression analysis showed that after adjustment for sex, age, diabetic duration, body mass index (BMI), plasma lipid status, HbA1c, systolic blood pressure (SBP), diastolic blood pressure (DBP), C-reactive protein and 24h-urinary albumin excreation, we showed that anemia was positive associated with DR, and the odds ratios (ORs) was 1.952 (95% CI 1.273~2.995; P=0.002). Conclusion Anemia is a critical risk factor of DR.

 

主管单位：上海市卫生健康委员会  主办单位：上海市医学会
©2025《上海医学》编辑部 沪ICP备09078599号
您是本站第26802659名访问者
网站管理