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冠状动脉多支病变不完全血运重建的疗效探讨
The effect of incomplete revascularization on the patients with multivessel coronary artery disease

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DOI:
作者:
李论 顾晔 胡立群 成忠 曾昆 胡勇钧 高波 邹武松
Li Lun,Gu Ye, Hu Liqun,Cheng Zhong,Zeng Kun,Hu Yon
作者单位:
华中科技大学附属武汉市普爱医院心内科
Department of Cardiology,Wuhan Puai Hospital,Huazhong University Of Science and Technology
关键词:
冠状动脉多支病变 不完全性血运重建 预后
Muhivessel coronary artery disease; Incomplete revascularization; Prognosis
摘要:
目的 探讨不完全性血运重建术对冠状动脉多支病变患者疗效及预后的影响。方法 113例经造影确诊冠状动脉多支病变患者，根据患者意愿分为两组：60例行冠状动脉不完全性血运重建术患者为不完全血运重建组(incomplete revascularization，IR)，53例行药物保守治疗患者为保守治疗组（conservative treatment ,CT）。随访12月对比两组患者左室射血分数(LVEF)、心绞痛发作、6分钟步行试验改善情况，并收集再入院次数、心脑血管MACE事件及死亡率进行统计学分析。结果 随访结束时心绞痛发作、EF值、6分钟步行试验前后对比IR组明显改善（p<0.05）而在CT组则在EF值、6分钟步行试验上均有恶化趋势达差异（p<0.05）,心绞痛发作无统计学意义（p＝0.053）;组间对比一年后心绞痛发作、6分钟步行试验、EF值、再入院次数IR组明显优于CT组（p<0.05），MACE事件及死亡率两组之间无统计学差异(p>0.05)。结论 冠状动脉多支病变行不完全性血运重建能够改善患者症状，提高其生活质量，但对于其预后的影响还需进一步研究明确
Objiective To investigate the effect of incomplete revascularization on the patients with multivessel coronary artery disease.Methods One hundred and thirteen patients with multivessel coronary artery disease had been divided into two groups by the wishes of themselves. One group included sixty patients underwent PCI with incomplete revascularization been called incomplete revascularization(IR);The other group included fifty-three patients only received drug treatment called conservative treatment(CT)．The long-term follow-up outcome for about 12 months were analyzed between the two groups by left ventricular ejection fraction(LVEF)、angina、six-minute walk test and readmission、MACE、mortality. Results To compare the end with the start in IR group ,LVEF、angina and six-minute walk test been mended (p<0.05);In CT group,LVEF、six-minute walk test been deteriorated(p<0.05),the different of angina had no statistical significance(p=0.053). To compare the two groups by the end of the follow-up visit, IR group preponderated over CT group in LVEF、angina、six-minute walk test and readmission (p<0.05) ; MACE and mortality had no statistical significance between the two groups(p>0.05). Conclusion The patients with multivessel coronary artery disease undergo PCI with incomplete revascularization can relieve the symptoms and improve the quality of life,but the effect on prognosis need more investigate.

 

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